Have you ever seen animals with blue blood? Although this sounds unusual, blue blood animals do exist. While most vertebrates (including humans) have red blood cells due to hemoglobin, some have blue blood cells due to the copper-based protein blood cyanate.
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This unique adaptability allows these organisms to thrive in specific environments, such as deep seas or low oxygen habitats. Here is a list of ten outstanding animals with blue blood and circulatory insights.
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Why blue blood?
Hyperamine uses copper ions to bind oxygen, which makes the blood blue when oxygenated. Unlike hemoglobin, which uses iron, hemoglobin is more effective in cold or hypoxic conditions, making it very suitable for these animals.
10 blue-blooded animals
- Horseshoe crab: Known for the importance of biomedical science, its blue blood contains blood cyanobacterase, used to detect bacterial endotoxins.
- Octopus: Equipped with three hearts and nine brains, their blue blood helps them survive deep in the cold sea.
- Squid: Similar to octopus, squid has a complex circulation system with three hearts and blood rich in hemocyanin.
- Spiders: Their pale blue hemolymph flows freely through the open circulation system.
- Lobsters: Their blood turns blue when oxygenated and flows through the single-ventricular heart.
- Clams: These bivalves have an open circulation system and use hemoanine for oxygen delivery.
- Scallops: Like clams, scallops have an open circulation system and a turquoise blood.
- Cuttlefish: closely related to squid and octopus, they rely on hemocyanin for oxygen transport in the three heart system.
- Amazon Milk Frogs: Their blue blood is colored by bislipoprotein rather than hemocyanin, making them unique among frogs.
- Brachiopods: These marine animals use hegerythrin instead of hemocystin, resulting in light yellow blood that appears blue under certain conditions.
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animal |
Circulation system |
Blood protein |
Unique features |
horseshoe crab |
Open |
Hemoglobin |
Biomedical applications |
octopus |
closure |
Hemoglobin |
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squid |
closure |
Hemoglobin |
Complex three-heart system |
spider |
Open |
Hemoglobin |
Light blue hemolymph |
lobster |
Open |
Hemoglobin |
Single ventricular center |
Clam |
Open |
Hemoglobin |
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scallop |
Open |
Hemoglobin |
Free swimming ability |
squid |
closure |
Hemoglobin |
Anatomy of late cephalopods |
Amazon Milk Frog |
closure |
biliverdin |
Blue color of bile pigment |
Brachiopod |
Open |
hemerythrin |
Shell-like structure |
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Category: Optical Illusion